Primary endpoints should center on pain and function Knee Injury and Osteoarthritis Outcome Score (KOOS), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), Patient-Reported Outcome Measurement Information System (PROMIS) scores), structure (MRI evaluation with delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) when appropriate), and time to milestones (return to sport)
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Here is what the evidence supports: Daily multivitamin: The baseline recommendation from multiple medical organizations for anyone on GLP-1 or GIP agonists
In other words, if you come back for treatment before the benefits have gone away, you will notice the effects to last longer and longer over time